I used Vitamin B1 for my cat's thiamine deficiency, reducing seizures and improving his neurological health effectively.
Vitamin B1 supplementation significantly reduced my cat's seizure episodes and improved his disorientation caused by thiamine deficiency, using a simple water-dissolved dosing technique he tolerates well.
This is a review of product:
Superior Source B-1 100 mg - Vitamin B Supplement Supports Healthy Energy & Growth - Nervous & Digestive System Support Formula with Thiamin - 100 Sublingual Dissolving Tablets
From Amazon.com
I have a 14-15 year old cat that developed seizures after getting a convenia shot this past winter, being on an rx kibble for struvites, and metronidazole for a c.perfringens infection over the winter and spring. Both drugs and the d-methionine in the kibble to lower urine ph lower the seizure threshold. It wasn't until he was given just two doses of the metronidazole that the seizures manifested clearly and scarily ~ tonic clonic aka grand mal seizures. Looking back to the winter his symptoms appear to be seizures. Seizure meds have helped for the most part but he's still having too many periods of him looking out of it and lost and walking around in circles which point to absent seizures aka petit mal seizures. He's on a keto diet with MCT oil to help with the seizures but we just started the MCT oil about 3 weeks ago. We've added homeopathic remedies and an herbal remedy for pets specifically for seizures which bring him out of it for a while. My daughter who spends the majority of time with him has been researching (as have I) and stumbled across a case study of two cats presenting with seizures due to thiamine deficiency. Both recovered quickly after B1 injections. As well as another article written by a woman who suffers from metronidazole toxicity and found that she had a thiamine deficiency that contributed greatly to her symptoms, one of which was a slightly enlarged heart (the vet has detected a grade 1-2 murmur which is also a thiamine deficiency symptom). So I got this to give it a try. We are starting at a lower cat-sized dose since he appears to be sensitive to everything. I cannot even give him CoQ10 for his heart since it triggers seizures. Anyways we're on day 2 of supplementing so too soon to tell if it's helping. I dissolved a couple of tablets in water in 10 mls of water in a small brown glass bottle and keep in the fridge. To dose him I pull the amount I want (this morning was 25mg ~ so 1.5ml) into a dosing syringe and squirt it down his throat. He doesn't seem to mind it. I guess he's gotten used to all the supplements we've been giving him. I also got the b-complex by the same company for kids to make sure he's not getting depleted in the other b's. I just put the tablet in a dosing syringe and pull in a mil or two of water to squirt down his throat so it's over quick.
So people who are having problems getting past the bitterness or taste of the b100, they can try what we've been doing. Dissolve the tablet in a small amount of water (1 teaspoon or less) and then hold your breath and put it in your mouth and let it absorb into your mouth. Holding your breath will help blunt the taste. Follow up with a sip of water.
Vitamin Basics & Tips
Thiamine Deficiency in Pets
Thiamine (Vitamin B1) deficiency disrupts energy metabolism in brain cells. Cats can't synthesize it and rely on diet. Symptoms include seizures, circling, heart murmurs, and confusion. This often stems from poor diet, certain medications, or malabsorption.
Metronidazole Toxicity Connection
Metronidazole, an antibiotic for bacterial infections, depletes thiamine by inhibiting its conversion to active form. Prolonged use lowers seizure thresholds and causes neurotoxicity. Symptoms mimic thiamine deficiency, requiring B1 supplementation for recovery.
Seizure Types Explained
Tonic-clonic (grand mal) seizures involve muscle rigidity and convulsions. Absence (petit mal) seizures show as disorientation and circling. Both types may indicate thiamine deficiency or drug toxicity in cats, often improved with B1.
B Vitamin Synergy
Thiamine works with other B vitamins for neurological health. B-complex prevents deficiencies when supplementing B1 long-term. Deficiencies in B6 or B12 can worsen neurological symptoms despite adequate thiamine levels.
Administering Supplements to Pets
Dissolve tablets in water and use syringes for precise dosing. Refrigerate solutions for stability. Mask bitterness by quick throat administration. Start with low doses for sensitive animals, monitoring reactions closely.
Dietary Support Strategies
Keto diets with MCT oil may aid seizure management but require veterinary supervision. Avoid foods with thiaminase enzymes (raw fish). Cooked eggs, legumes, and fortified grains boost natural B1 intake.
FAQs: Vitamin B1 for Pets
Safe dosage for cats? Typical dose is 25-100mg daily. Always consult your vet.
How quickly does it work? Neurological improvements may appear within days.
Signs of overdose? Excess B1 is excreted urine. No known toxicity.
Human vs pet supplements? Human supplements are safe with adjusted dosing.
Interactions with medications? May reduce efficacy of certain antibiotics. Inform your vet.
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